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Secondary antibodies where hamster is the host species. Secondary antibodies must be raised against the host species of the primary antibody. Includes different antigens, classifications, conjugations, and isotypes.
The protein encoded by this gene is essential for T-cell proliferation and survival cytokine production and T-helper type-2 development Several alternatively spliced transcript variants encoding different isoforms have been found for this gene
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The protein encoded by this gene is essential for T-cell proliferation and survival cytokine production and T-helper type-2 development Several alternatively spliced transcript variants encoding different isoforms have been found for this gene
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Enables protein kinase binding activity Acts upstream of or within several processes including positive regulation of immune response positive regulation of intracellular signal transduction and regulation of lymphocyte activation Located in external side of plasma membrane and immunological synapse Human ortholog(s) of this gene implicated in multiple sclerosis and type 1 diabetes mellitus Orthologous to human CD28 (CD28 molecule)
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Enables protein kinase binding activity Acts upstream of or within several processes including positive regulation of immune response positive regulation of intracellular signal transduction and regulation of lymphocyte activation Located in external side of plasma membrane and immunological synapse Human ortholog(s) of this gene implicated in multiple sclerosis and type 1 diabetes mellitus Orthologous to human CD28 (CD28 molecule)
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Enables protein kinase binding activity Acts upstream of or within several processes including positive regulation of immune response positive regulation of intracellular signal transduction and regulation of lymphocyte activation Located in external side of plasma membrane and immunological synapse Human ortholog(s) of this gene implicated in multiple sclerosis and type 1 diabetes mellitus Orthologous to human CD28 (CD28 molecule)
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Enables protein kinase binding activity Acts upstream of or within several processes including positive regulation of immune response positive regulation of intracellular signal transduction and regulation of lymphocyte activation Located in external side of plasma membrane and immunological synapse Human ortholog(s) of this gene implicated in multiple sclerosis and type 1 diabetes mellitus Orthologous to human CD28 (CD28 molecule)
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Enables protein kinase binding activity Acts upstream of or within several processes including positive regulation of immune response positive regulation of intracellular signal transduction and regulation of lymphocyte activation Located in external side of plasma membrane and immunological synapse Human ortholog(s) of this gene implicated in multiple sclerosis and type 1 diabetes mellitus Orthologous to human CD28 (CD28 molecule)
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Enables protein kinase binding activity Acts upstream of or within several processes including positive regulation of immune response positive regulation of intracellular signal transduction and regulation of lymphocyte activation Located in external side of plasma membrane and immunological synapse Human ortholog(s) of this gene implicated in multiple sclerosis and type 1 diabetes mellitus Orthologous to human CD28 (CD28 molecule)
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Enables protein kinase binding activity Acts upstream of or within several processes including positive regulation of immune response positive regulation of intracellular signal transduction and regulation of lymphocyte activation Located in external side of plasma membrane and immunological synapse Human ortholog(s) of this gene implicated in multiple sclerosis and type 1 diabetes mellitus Orthologous to human CD28 (CD28 molecule)
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells The protein contains a V domain a transmembrane domain and a cytoplasmic tail Alternate transcriptional splice variants encoding different isoforms have been characterized The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond while the soluble isoform functions as a monomer Mutations in this gene have been associated with insulin-dependent diabetes mellitus Graves disease Hashimoto thyroiditis celiac disease systemic lupus erythematosus thyroid-associated orbitopathy and other autoimmune diseases
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CD152 also known as CTLA-4 or Ly-56 is a 33 kDa member of the immunoglobulin superfamily It is expressed on activated T and B lymphocytes CD152 exhibits significant homology to CD28 in amino acid sequence structural configuration and genomic organization with both receptors sharing ligands from the B7 family (B7-1 and B7-2) While CD28 delivers co-stimulatory signals during T cell activation CTLA-4 functions as a critical negative regulator of cell-mediated immune responses CD152 is implicated in the induction and maintenance of immune tolerance the development of protective immunity and the modulation of thymocyte homeostasis
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Enables protein kinase binding activity Acts upstream of or within several processes including positive regulation of immune response positive regulation of intracellular signal transduction and regulation of lymphocyte activation Located in external side of plasma membrane and immunological synapse Human ortholog(s) of this gene implicated in multiple sclerosis and type 1 diabetes mellitus Orthologous to human CD28 (CD28 molecule)
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More